Is concomitant use of salbutamol (albuterol) permitted?

Yes, there are no restrictions on the use of salbutamol. We have occasionally seen it indicated as a treatment for either cough or IPF but in practice it is being used to manage co-existing bronchoconstriction rather than either cough or the underlying disease.

Corticosteriods – most studies provide guidance on maximum daily dose. Any guidance for this study? Or is the only requirement is that it is stable for 2 weeks prior and patients remain on same dose?

The guidance on corticosteroids in other studies was something of a hang-over from the days before the disease modifying therapies became available and steroids were used in combination therapy to try to control the disease in the absence of any other options. As they are no longer recommended and less widely used there is no […]